Bradley Kerr Selected Research

lesinurad

1/2019	Lesinurad: Evaluation of Pharmacokinetic and Pharmacodynamic Interactions With Warfarin in Healthy Volunteers.
1/2018	The Effect of Lesinurad in Combination With Allopurinol on Serum Uric Acid Levels in Patients With Gout.
7/2017	Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and CYP Enzyme Substrates Sildenafil, Amlodipine, Tolbutamide, and Repaglinide.
7/2017	Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and Commonly Used Drugs for Gout Treatment.
1/2016	Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers.
1/2016	Supratherapeutic dose evaluation and effect of lesinurad on cardiac repolarization: a thorough QT/QTc study.
12/2014	Pharmacodynamic, pharmacokinetic and tolerability evaluation of concomitant administration of lesinurad and febuxostat in gout patients with hyperuricaemia.

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Bradley Kerr Research Topics

Disease

7	Gout 01/2019 - 12/2014
4	Hyperuricemia 01/2019 - 07/2017
2	Neuralgia (Stump Neuralgia) 01/2017 - 11/2010
2	Pain (Aches) 01/2015 - 01/2015
1	Hypersensitivity (Allergy) 01/2017
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2017
1	Chronic Pain 01/2015
1	Peripheral Nervous System Diseases (PNS Diseases) 11/2010
1	HIV Infections (HIV Infection) 11/2010

Drug/Important Bio-Agent (IBA)

7	Xanthine OxidaseIBA 01/2019 - 12/2014
7	lesinuradIBA 01/2019 - 12/2014
7	Uric Acid (Urate)IBA 01/2019 - 12/2014
2	Colchicine FDA LinkGeneric 07/2017 - 12/2014
2	NeurosteroidsIBA 01/2015 - 01/2015
1	coumarinIBA 01/2019
1	Warfarin (Coumadin)FDA LinkGeneric 01/2019
1	AnticoagulantsIBA 01/2019
1	Allopurinol (Remid)FDA LinkGeneric 01/2018
1	Naproxen (Naprosyn)FDA LinkGeneric 07/2017
1	Indomethacin (Indometacin)FDA LinkGeneric 07/2017
1	Messenger RNA (mRNA)IBA 01/2017
1	ChloridesIBA 01/2017
1	Bumetanide (Bumex)FDA LinkGeneric 01/2017
1	SymportersIBA 01/2017
1	Amino Acids FDA Link 01/2015
1	Aminobutyrates (Aminobutyric Acid)IBA 01/2015
1	Biogenic Amines (Biogenic Amine)IBA 01/2015
1	Biological ProductsIBA 01/2015
1	Dopamine (Intropin)FDA LinkGeneric 01/2015
1	gamma-Aminobutyric Acid (GABA)IBA 01/2015
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2015
1	Serotonin (5 Hydroxytryptamine)IBA 01/2015
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2015
1	Glutamic Acid (Glutamate)FDA Link 01/2015
1	Febuxostat FDA Link 12/2014
1	vpr Gene ProductsIBA 11/2010
1	CalciumIBA 11/2010
1	CytokinesIBA 11/2010
1	InterferonsIBA 11/2010

Therapy/Procedure

2	Therapeutics 01/2018 - 12/2014